CD40 Antikörper (AA 1-360)

Produktnummer ABIN3030398

Der Kaninchen Polyklonal Anti-CD40-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, CD40 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für CD40 Antikörper (AA 1-360) (ABIN3030398)

Target: CD40

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD40 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CD40 Antikörper

Bindungsspezifität: AA 1-360

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 1-360) was used as the immunogen for this p50 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Titration of the p50 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: The p50 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeat freeze/thaws.

Details zu CD40

Target: CD40

Andere Bezeichnung: p50

Hintergrund: Nuclear factor NF-kappa-B p105/p50, also called EBP-1 is a protein that in humans is encoded by the NFKB1 gene. By fluorescence in situ hybridization, the gene was assigned to human chromosome 4q24. NFKB1 is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NFKB1 proteins by p105 and generation of p50 by a cotranslational processing.

Gen-ID: 4790

Pathways: NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints