IFNA Antikörper

Produktnummer ABIN3026804

Dieses Maus Monoklonal-Antikörper erkennt spezifisch IFNA in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IFNA Antikörper (ABIN3026804)

Target: IFNA (Interferon alpha (IFNA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IFNA Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 2-52

Produktdetails anti-IFNA Antikörper

Produktmerkmale: This mAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

Aufreinigung: Protein G affinity chromatography

Immunogen: Purified recombinant human IFNA1 was used as the immunogen for the Interferon alpha antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Interferon alpha antibody should be determined by the researcher.\. ELISA: order BSA/azide-free format for coating

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Interferon alpha antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu IFNA

Target: IFNA (Interferon alpha (IFNA))

Andere Bezeichnung: Interferon alpha

Hintergrund: This mAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

Pathways: JAK-STAT Signalweg, TLR Signalweg, Hepatitis C, Inflammasome