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PCNA Antikörper (AA 1-261)

Der Kaninchen Polyklonal Anti-PCNA-Antikörper wurde für WB, IHC, IF und IP validiert. Er ist geeignet, PCNA in Proben von Human zu detektieren. Es sind 3+ Publikationen verfügbar.
Produktnummer ABIN3020826

Kurzübersicht für PCNA Antikörper (AA 1-261) (ABIN3020826)

Target

Alle PCNA Antikörper anzeigen
PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Reaktivität

  • 243
  • 166
  • 165
  • 55
  • 32
  • 30
  • 29
  • 22
  • 20
  • 19
  • 18
  • 17
  • 11
  • 10
  • 6
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 142
  • 117
  • 3
Kaninchen

Klonalität

  • 139
  • 122
  • 1
Polyklonal

Konjugat

  • 143
  • 17
  • 11
  • 8
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PCNA Antikörper ist unkonjugiert

Applikation

  • 218
  • 79
  • 68
  • 67
  • 65
  • 55
  • 53
  • 46
  • 40
  • 40
  • 15
  • 12
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
  • Bindungsspezifität

    • 16
    • 16
    • 16
    • 15
    • 14
    • 13
    • 12
    • 9
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-261

    Sequenz

    MFEARLVQGS ILKKVLEALK DLINEACWDI SSSGVNLQSM DSSHVSLVQL TLRSEGFDTY RCDRNLAMGV NLTSMSKILK CAGNEDIITL RAEDNADTLA LVFEAPNQEK VSDYEMKLMD LDVEQLGIPE QEYSCVVKMP SGEFARICRD LSHIGDAVVI SCAKDGVKFS ASGELGNGNI KLSQTSNVDK EEEAVTIEMN EPVQLTFALR YLNFFTKATP LSSTVTLSMS ADVPLVVEYK IADMGHLKYY LAPKIEDEEG S

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human PCNA (NP_002583.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid freeze / thaw cycles

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Liu, Wang, Han, Cheng, Hu, Zhang: "Enhanced proliferation and differentiation of HO-1 gene-modified bone marrow-derived mesenchymal stem cells in the acute injured kidney." in: International journal of molecular medicine, Vol. 42, Issue 2, pp. 946-956, (2018) (PubMed).

    Wang, Sun, Zhu, Sun, Ma, Wang, Lu, Chen, Xu: "Quantitative proteomic analysis revealed changes in protein synthesis and mitochondrial functions after acute DNA damage in mouse neural stem cells." in: Neuroscience letters, Vol. 653, pp. 355-361, (2018) (PubMed).

    Lin, Wang, Zou, Sun, Liu, Zhao, Wang, Jin: "The Influenza Virus H5N1 Infection Can Induce ROS Production for Viral Replication and Host Cell Death in A549 Cells Modulated by Human Cu/Zn Superoxide Dismutase (SOD1) Overexpression." in: Viruses, Vol. 8, Issue 1, (2016) (PubMed).

  • Target

    PCNA (Proliferating Cell Nuclear Antigen (PCNA))

    Andere Bezeichnung

    PCNA

    Hintergrund

    The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.,PCNA,ATLD2,Epigenetics & Nuclear Signaling,Cancer,Tumor biomarkers,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Cell Cycle,Stem Cells,PCNA

    Molekulargewicht

    28 kDa

    Gen-ID

    5111

    UniProt

    P12004

    Pathways

    Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagie
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