SMAD4 Antikörper (pThr277)
Kurzübersicht für SMAD4 Antikörper (pThr277) (ABIN2794149)
Target
Alle SMAD4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pThr277
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Verwendungszweck
- Rabbit Anti-Human Phospho-SMAD4(T277) Antibody
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Immunogen
- This SMAD4 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T277 of human SMAD4.
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Isotyp
- Ig Fraction
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Applikationshinweise
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Immunofluorescence, Dot Blot, Immunohistochemistry
Recommended Dilutions
IF: 1:10-50, DB: 1:500, IHC: 1:10-50Confocal immunofluorescent analysis of Phospho-SMAD4-T277 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- SMAD4 (SMAD Family Member 4 (SMAD4))
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Andere Bezeichnung
- SMAD4
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Hintergrund
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Target Description: Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.
Gene Symbol: SMAD4
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Molekulargewicht
- 60439 Da
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Gen-ID
- 4089
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UniProt
- Q13485
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Pathways
- Zellzyklus, Chromatin Binding, Autophagie
Target
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