GIP Antikörper (N-Term)

Produktnummer ABIN2793043

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GIP in WB, IHC und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für GIP Antikörper (N-Term) (ABIN2793043)

Target: GIP (Gastric Inhibitory Polypeptide (GIP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-GIP Antikörper

Bindungsspezifität: AA 7-38, N-Term

Verwendungszweck: Rabbit Anti-Human GIPR (N-term) Antibody

Immunogen: This GIPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-38 amino acids from the N-terminal region of human GIPR.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, FC: 1:10-50Western blot analysis of GIPR antibody (N-term) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 2.000 mg/mL

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu GIP

Target: GIP (Gastric Inhibitory Polypeptide (GIP))

Andere Bezeichnung: GIP

Hintergrund:

Target Description: GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.

Gene Symbol: GIPR

Molekulargewicht: 53157 Da

Gen-ID: 2696

UniProt: P48546

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism