DIABLO Antikörper (C-Term)

Produktnummer ABIN2792127

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DIABLO in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Rind (Kuh), Hund, Pferd und Schwein.

Kurzübersicht für DIABLO Antikörper (C-Term) (ABIN2792127)

Target: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Reaktivität: Human, Rind (Kuh), Hund, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DIABLO Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-DIABLO Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: DIABLO Antibody - C-terminal region

Sequenz: LVKLQVEEVH QLSRKAETKL AEAQIEELRQ KTQEEGEERA ESEQEAYLRE

Homologie: Cow: 85%, Dog: 92%, Horse: 85%, Human: 100%, Pig: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against DIABLO. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DIABLO

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu DIABLO

Target: DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))

Andere Bezeichnung: DIABLO

Hintergrund:

Background Information: DIABLO is an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Several alternatively spliced transcript variants that encode distinct isoforms have been described for this gene but the validity of some transcripts, and their predicted ORFs, has not been determined conclusively.

Gene Name: Diablo, IAP-binding mitochondrial protein

Alternative Symbols: SMAC, DFNA64

Protein Name: Diablo homolog (Drosophila) EMBL AAH95468.1

Molekulargewicht: 21kDa

Gen-ID: 56616

NCBI Accession: NP_620308

UniProt: Q502X2

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity