IRAK4 Antikörper (C-Term)

Produktnummer ABIN2788803

Der Kaninchen Polyklonal anti-IRAK4 Antikörper (ABIN2788803) detektiert spezifisch IRAK4 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Pferd, Rind (Kuh), Schaf und Meerschweinchen.

Kurzübersicht für IRAK4 Antikörper (C-Term) (ABIN2788803)

Target: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Reaktivität: Human, Ratte, Pferd, Rind (Kuh), Schaf, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRAK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IRAK4 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: IRAK4 Antibody - C-terminal region

Sequenz: TGLPAVDEHR EPQLLLDIKE EIEDEEKTIE DYIDKKMNDA DSTSVEAMYS

Homologie: Cow: 77%, Guinea Pig: 91%, Horse: 92%, Human: 100%, Rat: 91%, Sheep: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against IRAK4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61431-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu IRAK4

Target: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Andere Bezeichnung: IRAK4

Hintergrund:

Background Information: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: Interleukin-1 receptor-associated kinase 4

Alternative Symbols: IPD1, IMD67, REN64, IRAK-4, NY-REN-64

Protein Name: Interleukin-1 receptor-associated kinase 4

Molekulargewicht: 36kDa

Gen-ID: 51135

NCBI Accession: NP_001138728

UniProt: Q9NWZ3

Pathways: NF-kappaB Signalweg, TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades