IRAK4 Antikörper (C-Term)

Produktnummer ABIN2788803

Dieses Anti-IRAK4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IRAK4 in WB. Geeignet für Human, Ratte, Rind (Kuh), Pferd, Schaf und Meerschweinchen.

Kurzübersicht für IRAK4 Antikörper (C-Term) (ABIN2788803)

Target: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Reaktivität: Human, Ratte, Rind (Kuh), Pferd, Schaf, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRAK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IRAK4 Antikörper

Bindungsspezifität: C-Term

Sequenz: TGLPAVDEHR EPQLLLDIKE EIEDEEKTIE DYIDKKMNDA DSTSVEAMYS

Homologie: Cow: 77%, Guinea Pig: 91%, Horse: 92%, Human: 100%, Rat: 91%, Sheep: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against IRAK4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 336 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IRAK4

Target: IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))

Andere Bezeichnung: IRAK4

Hintergrund: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: IPD1, NY-REN-64, REN64, IRAK-4
Protein Interaction Partner: MYD88, IRAK1, IKBKG, SASH1, ARNT, TNFRSF13B, IL1RL1, TRAF6, PELI1, PELI2, IL1R1, MBP, HIST1H1A, HIST1H1T, HIST1H1B, HIST1H1E, HIST1H1D, HIST1H1C, EIF4EBP1, TIRAP, IRAK3, IRAK2, TLR4, TICAM2, TBPL1, PELI3, UBC,
Protein Size: 336

Molekulargewicht: 36 kDa

Gen-ID: 51135

NCBI Accession: NM_001145256, NP_001138728

Pathways: NF-kappaB Signalweg, TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades