OGG1 Antikörper (C-Term)
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- Target Alle OGG1 Antikörper anzeigen
- OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
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Bindungsspezifität
- C-Term
- Reaktivität
- Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser OGG1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- AVPVDVHMWH IAQRDYSWHP TTSQAKGPSP QTNKELGNFF RSLWGPYAGW
- Spezifität
- Directed against isoforms 2D, 1A, 1B, 2E.
- Homologie
- Cow: 93%, Dog: 100%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 92%, Rat: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against OGG1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product OGG1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 345 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
- Andere Bezeichnung
- OGG1 (OGG1 Produkte)
- Synonyme
- OGG1 antikoerper, zgc:158858 antikoerper, 8-oxoguanine-DNA glycosylase 1 antikoerper, ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1 antikoerper, ATOGG1 antikoerper, F8K7.14 antikoerper, F8K7_14 antikoerper, 19.m02329 antikoerper, DDBDRAFT_0184479 antikoerper, DDBDRAFT_0233024 antikoerper, DDB_0184479 antikoerper, DDB_0233024 antikoerper, ogg1 antikoerper, Tb04.1H19.930 antikoerper, HMMH antikoerper, HOGG1 antikoerper, MUTM antikoerper, OGH1 antikoerper, Mmh antikoerper, 8-oxoguanine DNA glycosylase antikoerper, 8-oxoguanine DNA glycosylase L homeolog antikoerper, 8-oxoguanine-DNA glycosylase 1 antikoerper, 8-OXOGUANINE DNA GLYCOSYLASE antikoerper, putative 8-oxoguanine DNA glycosylase antikoerper, 8-oxoguanine DNA-glycosylase antikoerper, N-glycosylase/DNA lyase OGG1 antikoerper, 8-oxoguanine DNA-glycosylase 1 antikoerper, OGG1 antikoerper, ogg1.L antikoerper, ogg1 antikoerper, ECU08_0770 antikoerper, CA_C2707 antikoerper, BBOV_I004290 antikoerper, Smp_074010.1 antikoerper, LOC9329243 antikoerper, Tb927.4.2480 antikoerper, Ogg1 antikoerper
- Hintergrund
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This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization.
Alias Symbols: HMMH, HOGG1, MUTM, OGH1
Protein Interaction Partner: ERCC6, ERCC8, UBC, Ogg1, CHGB, XRCC1, PRKCA, SNRPF,
Protein Size: 345 - Molekulargewicht
- 38 kDa
- Gen-ID
- 4968
- NCBI Accession
- NM_016829, NP_058438
- UniProt
- O15527
- Pathways
- DNA Reparatur
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