OGG1 Antikörper (AA 151-250)

Produktnummer ABIN702655

Produktdetails anti-OGG1 Antikörper

Target: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Bindungsspezifität: AA 151-250

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OGG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OGG1/8 hydroxyguanine DNA glycosylase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-OGG1 Antikörper (ABIN702655)

Cogoi, Ferino, Miglietta, Pedersen, Xodo: "The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription." in: Nucleic acids research, Vol. 46, Issue 2, pp. 661-676, (2017) (PubMed).

Details zu OGG1

Target: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Andere Bezeichnung: OGG1 (OGG1 Produkte)

Synonyme: OGG1 antikoerper, zgc:158858 antikoerper, 8-oxoguanine-DNA glycosylase 1 antikoerper, ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1 antikoerper, ATOGG1 antikoerper, F8K7.14 antikoerper, F8K7_14 antikoerper, 19.m02329 antikoerper, DDBDRAFT_0184479 antikoerper, DDBDRAFT_0233024 antikoerper, DDB_0184479 antikoerper, DDB_0233024 antikoerper, ogg1 antikoerper, Tb04.1H19.930 antikoerper, HMMH antikoerper, HOGG1 antikoerper, MUTM antikoerper, OGH1 antikoerper, Mmh antikoerper, 8-oxoguanine DNA glycosylase antikoerper, 8-oxoguanine DNA glycosylase L homeolog antikoerper, 8-oxoguanine-DNA glycosylase 1 antikoerper, 8-OXOGUANINE DNA GLYCOSYLASE antikoerper, putative 8-oxoguanine DNA glycosylase antikoerper, 8-oxoguanine DNA-glycosylase antikoerper, N-glycosylase/DNA lyase OGG1 antikoerper, 8-oxoguanine DNA-glycosylase 1 antikoerper, OGG1 antikoerper, ogg1.L antikoerper, ogg1 antikoerper, ECU08_0770 antikoerper, CA_C2707 antikoerper, BBOV_I004290 antikoerper, Smp_074010.1 antikoerper, LOC9329243 antikoerper, Tb927.4.2480 antikoerper, Ogg1 antikoerper

Hintergrund:

Synonyms: 8 hydroxyguanine DNA glycosylase, 8 oxoguanine DNA glycosylase 1, 8-oxoguanine DNA glycosylase, AP lyase, DNA apurinic or apyrimidinic site lyase, DNA lyase, DNA-apurinic or apyrimidinic site lyase, HMMH, HOGG 1, HOGG1, MMH, MUTM, N-glycosylase, Ogg 1, OGH 1, OGH1, OGG1_HUMAN.

Background: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008].

Gen-ID: 4968

Pathways: DNA Reparatur