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AKR1C1 Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-AKR1C1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, AKR1C1 in Proben von Human, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen und Schwein zu detektieren.
Produktnummer ABIN2788358

Kurzübersicht für AKR1C1 Antikörper (N-Term) (ABIN2788358)

Target

Alle AKR1C1 (DDH) Antikörper anzeigen
AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Reaktivität

  • 36
  • 10
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Schwein

Wirt

  • 29
  • 7
Kaninchen

Klonalität

  • 32
  • 4
Polyklonal

Konjugat

  • 25
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser AKR1C1 Antikörper ist unkonjugiert

Applikation

  • 23
  • 12
  • 11
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    LERSLKNLQL DYVDLYLIHF PVSVKPGEEV IPKDENGKIL FDTVDLCATW

    Homologie

    Cow: 86%, Dog: 77%, Horse: 77%, Human: 100%, Pig: 77%, Rabbit: 82%, Rat: 82%

    Produktmerkmale

    This is a rabbit polyclonal antibody against AKR1C1. It was validated on Western Blot.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1C1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 323 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

    Andere Bezeichnung

    AKR1C1

    Hintergrund

    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
    Alias Symbols: 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DDH, DDH1, H-37, HAKRC, MBAB, MGC8954, HBAB, DD1/DD2
    Protein Interaction Partner: PTPN3, UBC, FN1, COMMD8, MAPK3, AKR1C1,
    Protein Size: 323

    Molekulargewicht

    36 kDa

    Gen-ID

    1645

    NCBI Accession

    NM_001353, NP_001344

    UniProt

    Q04828

    Pathways

    Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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