AXL Antikörper (C-Term)

Produktnummer ABIN2787910

Produktdetails anti-AXL Antikörper

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AXL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QPDPKDSCSC LTAAEVHPAG RYVLCPSTTP SPAQPADRGS PAAPGQEDGA

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 86%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against AXL. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AXL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 885 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AXL

Target: AXL (AXL Receptor tyrosine Kinase (AXL))

Andere Bezeichnung: AXL (AXL Produkte)

Hintergrund: The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: JTK11, UFO
Protein Interaction Partner: RANBP9, UBC, TYRO3, FBXO25, STUB1, HSP90AA1, HSPA1A, ERRFI1, TNK2, ELAVL1, CBL, SHC3, SOCS1, PIK3R2, ADAM10, SHC1, GAS6, SRC, PTPN11, PLCG1, PIK3R1, LCK, AXL, GRB2, TENC1, PIK3R3, NCK2,
Protein Size: 885

Molekulargewicht: 97 kDa

Gen-ID: 558

NCBI Accession: NM_001699, NP_001690

UniProt: P30530

Pathways: RTK Signalweg, Cellular Response to Molecule of Bacterial Origin