NLRP1 Antikörper (N-Term)

Produktnummer ABIN2785731

Der Kaninchen Polyklonal Anti-NLRP1 Antikörper wurde für WB validiert. Er ist geeignet, NLRP1 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Schwein und Kaninchen zu detektieren.

Kurzübersicht für NLRP1 Antikörper (N-Term) (ABIN2785731)

Target: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NLRP1 Antikörper

Bindungsspezifität: N-Term

Sequenz: DTQEPRIVIL QGAAGIGKST LARQVKEAWG RGQLYGDRFQ HVFYFSCREL

Homologie: Cow: 85%, Dog: 86%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 85%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NLRP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NLRP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1375 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NLRP1

Target: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Andere Bezeichnung: NLRP1

Hintergrund: This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like
Alias Symbols: CARD7, CLR17.1, DEFCAP, DEFCAP-L/S, DKFZp586O1822, KIAA0926, NAC, NALP1, PP1044, SLEV1, VAMAS1
Protein Interaction Partner: TRIM68, CUL3, APOA1, NLRP1, PYCARD, NOD1, CASP5, CASP9, APAF1, CASP2, BCL2L1, BCL2, CASP1, NLRC4,
Protein Size: 1375

Molekulargewicht: 155 kDa

Gen-ID: 22861

NCBI Accession: NM_001033053, NP_001028225

UniProt: Q9C000

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome