CD36 Antikörper (N-Term)

Produktnummer ABIN2783230

Der Kaninchen Polyklonal Anti-CD36-Antikörper wurde für WB und IHC validiert. Er ist geeignet, CD36 in Proben von Human, Ratte, Hund, Schwein, Kaninchen, Rind (Kuh), Ziege und Pferd zu detektieren.

Kurzübersicht für CD36 Antikörper (N-Term) (ABIN2783230)

Target: CD36

Reaktivität: Human, Ratte, Hund, Schwein, Kaninchen, Rind (Kuh), Ziege, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD36 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CD36 Antikörper

Bindungsspezifität: N-Term

Sequenz: MGCDRNCGLI AGAVIGAVLA VFGGILMPVG DLLIQKTIKK QVVLEEGTIA

Homologie: Cow: 79%, Dog: 79%, Goat: 79%, Horse: 79%, Human: 100%, Pig: 79%, Rabbit: 79%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against CD36. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CD36

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 472 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CD36

Target: CD36

Andere Bezeichnung: CD36

Hintergrund: CD36 is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in its gene cause platelet glycoprotein deficiency.The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Three alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Alias Symbols: CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3, BDPLT10
Protein Interaction Partner: CHRD, APP, CAND1, ITGA2B, MATK, SRC, THBS1, ITGB3, LYN, YES1, ITGA6, CD9, FYN, ITGB1, COL1A2, COL1A1, VLDLR, LDLR, HSD11B1,
Protein Size: 472

Molekulargewicht: 53 kDa

Gen-ID: 948

NCBI Accession: NM_001001547, NP_001001547

UniProt: P16671

Pathways: TLR Signalweg, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteine