SMAD4 Antikörper (N-Term)

Produktnummer ABIN2780673

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SMAD4 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Zebrafisch (Danio rerio), Ziege, Meerschweinchen, Pferd und Schaf.

Kurzübersicht für SMAD4 Antikörper (N-Term) (ABIN2780673)

Target: SMAD4 (SMAD Family Member 4 (SMAD4))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Zebrafisch (Danio rerio), Ziege, Meerschweinchen, Pferd, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMAD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SMAD4 Antikörper

Bindungsspezifität: N-Term

Sequenz: MDNMSITNTP TSNDACLSIV HSLMCHRQGG ESETFAKRAI ESLVKKLKEK

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SMAD4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 552 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SMAD4

Target: SMAD4 (SMAD Family Member 4 (SMAD4))

Andere Bezeichnung: SMAD4

Hintergrund: SMAD4 is one of the Smad family members, which are essential intracellular signalling components of the transforming growth factor-beta (TGF-beta) superfamily. Smad2 and Smad3 are structurally highly similar and mediate TGF-beta signals. Smad4 is distantl
Alias Symbols: DPC4, JIP, MADH4, MYHRS
Protein Interaction Partner: RASSF5, LMO4, SMAD3, SMAD2, SKIL, UBC, NEDD8, SUMO1, SMURF2, SMURF1, TRIM33, CRYAB, COPS5, NLK, OTUB1, SMAD9, UBE2I, FHL3, FHL2, FHL1, CSNK1D, TGFB1I1, SMAD1, NCOR1, SKI, KLF5, IRF7, IRF3, ZNF521, ZNF423, SOX12, SNRNP70, RPL28, RFX1, RELA, RALA, PSMD11, P
Protein Size: 552

Molekulargewicht: 60 kDa

Gen-ID: 4089

NCBI Accession: NM_005359, NP_005350

UniProt: Q13485

Pathways: Zellzyklus, Chromatin Binding, Autophagie