STAT1 Antikörper (N-Term)

Produktnummer ABIN2779897

Produktdetails anti-STAT1 Antikörper

Target: STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schaf, Schwein, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STAT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QLQSWFTIVA ETLQQIRQQL KKLEELEQKF TYEPDPITKN KQVLSDRTFL

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 85%, Horse: 86%, Human: 86%, Mouse: 100%, Pig: 86%, Rabbit: 93%, Rat: 100%, Sheep: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against STAT1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of mouse STAT1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 749 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu STAT1

Target: STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))

Andere Bezeichnung: STAT1 (STAT1 Produkte)

Hintergrund: Stat1 is a member of the STAT family. It can form homodimers to modulate the transcriptional repression of PPARgamma2 in adipocytes
Alias Symbols: AA408197, 2010005J02Rik
Protein Interaction Partner: Isg15, Sumo1, Zfp467, Stat1, Fbxo2, Mapk1, Ubc, Btrc, Atf3, Pdlim2, Stat3, Mllt10, SMURF2, SMURF1, TGFBR1, SMAD4, ACVR1, Il6st, Gfap, S100b, Ifng, Tbx21,
Protein Size: 749

Molekulargewicht: 82 kDa

Gen-ID: 20846

NCBI Accession: NM_009283, NP_033309

UniProt: P42225

Pathways: JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events