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Src Antikörper (N-Term)

Name: Src Antikörper (N-Term)
SKU: ABIN486941
Price: 150.78 EUR
Availability: InStock

Src Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated

WB Suggested Anti-SRC Antibody Titration: 0. (Src Antikörper (N-Term))

Western Blotting (WB) image for anti-Proto-oncogene tyrosine-protein kinase Src (Src) (N-Term) antibody (ABIN486941) (Src Antikörper (N-Term))

Host: Mouse Target Name: SRC Sample Tissue: Mouse Spleen Antibody Dilution: 1ug/ml (Src Antikörper (N-Term))

Host: Mouse Target Name: SRC Sample Tissue: Mouse Liver Antibody Dilution: 1ug/ml (Src Antikörper (N-Term))

4 Abbildungen

Produktnummer ABIN486941

Datenblatt (PDF)

Target Alle Src Antikörper anzeigen

Src (Proto-oncogene tyrosine-protein kinase Src (Src))
Bindungsspezifität
25

22

20

20

15

15

14

12

11

8

7

6

4

4

4

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reaktivität
213

138

119

10

9

7

5

5

5

4

3

2

1

1

1
Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen
Wirt
219

22

1
Kaninchen
Passende Sekundärantikörper
Klonalität
205

37
Polyklonal
Konjugat
124

17

15

12

9

7

4

4

4

4

4

4

4

4

4

4

4

3

3

2

2

2

2
Dieser Src Antikörper ist unkonjugiert
Applikation
183

119

65

55

53

34

30

24

23

12

9

7

4

3

3

1
Western Blotting (WB)

Sequenz

QTPSKPASAD GHRGPSAAFA PAAAEPKLFG GFNSSDTVTS PQRAGPLAGG

Homologie

Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale

This is a rabbit polyclonal antibody against SRC. It was validated on Western Blot.

Aufreinigung

Affinity Purified

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SRC

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Src Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

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Applikationshinweise

Optimal working dilutions should be determined experimentally by the investigator.

Kommentare

Antigen size: 536 AA

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freeze-thaw cycles.

Lagerung

-20 °C

Informationen zur Lagerung

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target

Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Andere Bezeichnung

SRC (Src Produkte)

Substanzklasse

Viral Protein

Hintergrund

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. SRC protein is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer.
Alias Symbols: ASV, SRC1, c-SRC, p60-Src
Protein Interaction Partner: PSMB9, POLR2L, POLR2K, POLR2J, POLR2I, POLR2H, POLR2G, POLR2F, POLR2E, POLR2D, POLR2C, POLR2B, POLR2A, NEDD4, MAPT, ESR1, CA3, ARRB2, UBC, SRC, SPRR2A, IKBKG, CBLC, ZNF658B, TLR4, RGS16, PTGER4, EGFR, ARRB1, TNFRSF1A, KHDRBS1, SYK, CD44, ENO1, ANXA7, PIK3
Protein Size: 536

Molekulargewicht

60 kDa

Gen-ID

6714

NCBI Accession

NM_005417, NP_005408

UniProt

P12931

Pathways

JAK-STAT Signalweg, Neurotrophin Signalübertragung, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagie, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling