BAD Antikörper (Middle Region)

Produktnummer ABIN2779311

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch BAD in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen und Pferd. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für BAD Antikörper (Middle Region) (ABIN2779311)

Target: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BAD Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: BAD Antibody - middle region

Sequenz: GAVEIRSRHS SYPAGTEDDE GMGEEPSPFR GRSRSAPPNL WAAQRYGREL

Homologie: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against BAD. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30278-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-BAD Antikörper (ABIN2779311)

Mishra, Thakur, Somal, Parmar, Yadav, Bharati, Bharti, Paul, Verma, Chouhan, Sharma, Singh, González, DOcchio, Sarkar et al.: "Expression and localization of angiopoietin family in buffalo ovarian follicles during different stages of development and modulatory role of angiopoietins on steroidogenesis and survival of cultured ..." in: Theriogenology, Vol. 86, Issue 7, pp. 1818-33, (2016) (PubMed).

Mishra, Parmar, Yadav, Reshma, Bharati, Bharti, Paul, Chouhan, Taru Sharma, Singh, Sarkar et al.: "Expression and localization of angiopoietin family in corpus luteum during different stages of oestrous cycle and modulatory role of angiopoietins on steroidogenesis, angiogenesis and survivability ..." in: Reproduction in domestic animals = Zuchthygiene, Vol. 51, Issue 6, pp. 855-869, (2016) (PubMed).

Details zu BAD

Target: BAD (BCL2-Associated Agonist of Cell Death (BAD))

Andere Bezeichnung: BAD

Hintergrund:

Background Information: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

Gene Name: BCL2-associated agonist of cell death

Alternative Symbols: BBC2, BCL2L8

Protein Name: Bcl2 antagonist of cell death

Molekulargewicht: 18kDa

Gen-ID: 572

NCBI Accession: NP_004313

UniProt: Q92934

Pathways: MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, Apoptose, Fc-epsilon Rezeptor Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events