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NPM1 Antikörper (N-Term)

Dieses Anti-NPM1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NPM1 in WB und IHC. Geeignet für Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Schwein, Pferd und Meerschweinchen. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.
Produktnummer ABIN2778260

Kurzübersicht für NPM1 Antikörper (N-Term) (ABIN2778260)

Target

Alle NPM1 Antikörper anzeigen
NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Reaktivität

  • 209
  • 99
  • 67
  • 12
  • 11
  • 9
  • 8
  • 8
  • 6
  • 3
  • 3
  • 1
  • 1
  • 1
Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Schwein, Pferd, Meerschweinchen

Wirt

  • 134
  • 101
  • 1
  • 1
Kaninchen

Klonalität

  • 131
  • 107
Polyklonal

Konjugat

  • 123
  • 19
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NPM1 Antikörper ist unkonjugiert

Applikation

  • 174
  • 142
  • 76
  • 71
  • 51
  • 37
  • 28
  • 27
  • 26
  • 26
  • 22
  • 7
  • 7
  • 7
  • 5
  • 5
  • 4
  • 3
  • 3
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 69
    • 22
    • 21
    • 15
    • 15
    • 8
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    DMDMSPLRPQ NYLFGCELKA DKDYHFKVDN DENEHQLSLR TVSLGAGAKD

    Homologie

    Cow: 93%, Dog: 100%, Guinea Pig: 77%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against NPM1. It was validated on Western Blot and immunohistochemistry.

    Aufreinigung

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human NPM1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 294 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Komorek, Kuppuswamy, Subramanian, Vijayalingam, Lomonosova, Zhao, Mymryk, Schmitt, Chinnadurai: "Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1/K2 transcription factors." in: Journal of virology, Vol. 84, Issue 6, pp. 2719-31, (2010) (PubMed).

    Lin, Coutinho-Mansfield, Wang, Pandit, Fu: "The splicing factor SC35 has an active role in transcriptional elongation." in: Nature structural & molecular biology, Vol. 15, Issue 8, pp. 819-26, (2008) (PubMed).

  • Target

    NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

    Andere Bezeichnung

    NPM1

    Hintergrund

    NPM1 is a member of Nucleophosmin (NPM) family. NPM is a ubiquitously expressed nucleolar phosphoprotein that continuously shuttles between the nucleus and cytoplasm
    Alias Symbols: B23, NPM
    Protein Interaction Partner: COX8A, NPM2, HUWE1, UBC, PA2G4, FUS, TP53, AURKA, SUMO2, SUMO3, ELF4, STAU1, CDKN2A, LGR4, SUMO1, MDM2, RPA3, RPA2, RPA1, ERG, rev, TRMT61A, OSBP, KPNA1, LIMCH1, ARMCX3, YWHAQ, PARK2, TARDBP, TUBA1C, TAB2, CEP152, DZIP1, COPG1, STK38, COPE, PARK7, AKAP11,
    Protein Size: 294

    Molekulargewicht

    33 kDa

    Gen-ID

    4869

    NCBI Accession

    NM_002520, NP_002511

    UniProt

    P06748

    Pathways

    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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