PDK2 Antikörper (Middle Region)
Kurzübersicht für PDK2 Antikörper (Middle Region) (ABIN2777433)
Target
Alle PDK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- ELFKNAMRAT VESHESSLIL PPIKVMVALG EEDLSIKMSD RGGGVPLRKI
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Homologie
- Cow: 77%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%, Zebrafish: 77%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PDK2. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PDK2
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 407 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
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Andere Bezeichnung
- PDK2
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Hintergrund
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PDK2 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Alias Symbols: PDHK2
Protein Interaction Partner: VSIG4, DLAT, ISOC2, HIC2, SGK1, PDK2, PDK1, PDHA1, PDHX, AKT1, HTT,
Protein Size: 407 -
Molekulargewicht
- 44 kDa
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Gen-ID
- 5164
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NCBI Accession
- NM_002611, NP_002602
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UniProt
- Q15119
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Pathways
- PI3K-Akt Signalweg, RTK Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt
Target
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