PYCARD Antikörper (C-Term)

Produktnummer ABIN2774827

Der Kaninchen Polyklonal Anti-PYCARD Antikörper wurde für WB validiert. Er ist geeignet, PYCARD in Proben von Human, Ratte, Schwein, Pferd und Kaninchen zu detektieren.

Kurzübersicht für PYCARD Antikörper (C-Term) (ABIN2774827)

Target: PYCARD (PYD and CARD Domain Containing (PYCARD))

Reaktivität: Human, Ratte, Schwein, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PYCARD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PYCARD Antikörper

Bindungsspezifität: C-Term

Sequenz: ALIARVTNVE WLLDALYGKV LTDEQYQAVR AEPTNPSKMR KLFSFTPAWN

Homologie: Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 86%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against PYCARD. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PYCARD

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 195 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PYCARD

Target: PYCARD (PYD and CARD Domain Containing (PYCARD))

Andere Bezeichnung: PYCARD

Hintergrund: Pycard is a cytosolic soluble protein that forms insoluble aggregates and enhances etoposide-induced apoptosis.
Alias Symbols: ASC, CARD5, MGC10332, TMS, TMS-1, TMS1
Protein Interaction Partner: PYCARD, EXOC5, SQSTM1, BECN1, UBC, RALB, IKBKB, CHUK, NLRP2, PYDC2, NLRP12, NLRP1, NLRC4, NLRP3, POP1, SRF, MEFV, PRKAR1A, CASP1,
Protein Size: 195

Molekulargewicht: 21 kDa

Gen-ID: 29108

NCBI Accession: NM_013258, NP_037390

UniProt: Q9ULZ3

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome