LY9 Antikörper

Produktnummer ABIN2749218

Der Maus Monoklonal Anti-LY9-Antikörper wurde für WB, FACS, IP, ICC und Func validiert. Er ist geeignet, LY9 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für LY9 Antikörper (ABIN2749218)

Target: LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LY9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Functional Studies (Func)

Klon: HLy9-25

Produktdetails anti-LY9 Antikörper

Verwendungszweck: Anti-Hu CD229 Purified Low Endotoxin

Spezifität: The mouse monoclonal antibody HLy9.25 (also known as HLy9.1.25) recognizes an extracellular epitope of CD229 / Ly9, a 100-120 kDa cell surface glycoprotein expressed on T and B cells.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Endotoxin-Niveau: Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.

Immunogen: CD299-transfected 300.19 pre-B cell line

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Functional application: Regulation of activation,
Flow cytometry: Recommended dilution: 6-10 μg/mL, positive control: peripheral blood lymphocytes.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen für anti-LY9 Antikörper (ABIN2749218)

de la Fuente, Tovar, Villamor, Zapater, Pizcueta, Campo, Bosch, Engel: "Molecular characterization and expression of a novel human leukocyte cell-surface marker homologous to mouse Ly-9." in: Blood, Vol. 97, Issue 11, pp. 3513-20, (2001) (PubMed).

Details zu LY9

Target: LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

Andere Bezeichnung: CD229

Hintergrund: Lymphocyte antigen 9,CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.,SLAMF3, LY9

Gen-ID: 4063

UniProt: Q9HBG7

Pathways: BCR Signaling