CD11b Antikörper

Produktnummer ABIN2742255

Dieses Anti-CD11b-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von CD11b in FACS, IHC, IP, IF, IHC (fro), ELISA, Func und BR. Geeignet für Human, Maus, Kaninchen, Pavian, Rhesusaffen, Schimpanse und Cynomolgus.

Kurzübersicht für CD11b Antikörper (ABIN2742255)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reaktivität: Human, Maus, Kaninchen, Pavian, Rhesusaffen, Schimpanse, Cynomolgus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD11b Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), ELISA, Functional Studies (Func), Blocking Reagent (BR)

Klon: M1-70

Produktdetails anti-CD11b Antikörper

Spezifität: Mouse ITGAM / CD11b

Aufreinigung: Protein G purified

Immunogen: B10 mouse spleen cells enriched for T lymphocytes.

Type of Immunogen: Cells

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Approved: Block, ELISA, Flo (0.5 - 1 μg/10 x10⁶), Func, IF (0.5 - 1 μg/mL), IHC, IHC-Fr (0.5 - 1 μg/mL), IP

Usage: CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin alpha-M (CD11b) combines with the Integrin beta-2 (CD18) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin alpha-M/beta-2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. ELISA: Order BSA-free antibody format for coating.

Kommentare:

Target Species of Antibody: Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2°C to 8°C.

Details zu CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Andere Bezeichnung: ITGAM / CD11b

Hintergrund: Name/Gene ID: ITGAM
Family: Integrin

Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

Gen-ID: 3684

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation