IGF1 Antikörper

Produktnummer ABIN2741686

Der Maus Monoklonal anti-IGF1 Antikörper (Klon M23) (ABIN2741686) detektiert spezifisch IGF1 in WB, IF, FACS und Func. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Kaninchen.

Kurzübersicht für IGF1 Antikörper (ABIN2741686)

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Reaktivität: Human, Maus, Ratte, Kaninchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IGF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Functional Studies (Func)

Klon: M23

Produktdetails anti-IGF1 Antikörper

Spezifität: Human IGF-I / IGF1

Aufreinigung: Protein G purified

Immunogen: Purified human IGF1 protein.

Type of Immunogen: Purified protein

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Approved: Flo (0.5 - 1 μg/10 x10⁶), Func, IF (1 - 2 μg/mL), WB (0.5 - 1 μg/mL)

Usage: This antibody is specific to IGF1 (Insulin like Growth Factor 1) and shows minimal cross-reaction with IGF11, Proinsulin, MSF, and Insulin. IGF1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF1B while isoform 2 is known as IGF1A. IGF1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of the IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon. ELISA: Order BSA-free format for coating.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2°C to 8°C.

Details zu IGF1

Target: IGF1 (Insulin-Like Growth Factor 1 (IGF1))

Andere Bezeichnung: IGF-I / IGF1

Hintergrund: Name/Gene ID: IGF1
Family: Hormone

Synonyms: IGF1, IGF-IA, IGF-IB, IGFI, IBP1, IGF-I, Insulin-like growth factor 1, Insulin-like growth factor I, Insulin-like growth factor IA, Insulin-like growth factor IB, Mechano growth factor, Somatomedin-C, IGF1A, MGF

Gen-ID: 3479

Pathways: RTK Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagie, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation