TRADD Antikörper

Produktnummer ABIN271966

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TRADD in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für TRADD Antikörper (ABIN271966)

Target: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRADD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TRADD Antikörper

Spezifität: This antibody detects endogenous levels ofTRADD protein. (region surrounding Leu282)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu TRADD

Target: TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

Andere Bezeichnung: TRADD

Hintergrund: TRADD (TNF R1 associated death domain) is a 34 kDa protein that associates with the death domains of both FAS and TNFR1 via their DDH regions. Over expression of TRADD leads to NFkB activation and apoptosis in the absence of TNF.Synonyms: TNFR1-associated DEATH domain protein, TNFRSF1A-associated via death domain, Tumor necrosis factor receptor type 1-associated DEATH domain protein

Molekulargewicht: approx. 35 kDa

Gen-ID: 8717

NCBI Accession: NP_003780

UniProt: Q15628

Pathways: NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Hepatitis C