IL-6 Antikörper (Biotin)

Produktnummer ABIN2689781

Dieser Ratte Monoklonal Antikörper detektiert spezifisch IL-6 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Maus. Es wurde in 3+ Publikationen zitiert.

Kurzübersicht für IL-6 Antikörper (Biotin) (ABIN2689781)

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL-6 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA

Klon: MP5

Produktdetails anti-IL-6 Antikörper (Biotin)

Produktmerkmale: The MP5-32C11 antibody reacts with mouse interleukin-6 (IL-6). The immunogen used to generate the MP5-32C11 hybridoma was recombinant mouse IL-6. This is a non-neutralizing antibody.

BD Pharmingen™ Biotin Rat Anti-Mouse IL-6 - Biotin - Clone MP5-32C11 - Isotype Rat IgG2a - Reactivity Ms - 0.5 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Recombinant mouse IL-6

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Referenzen für anti-IL-6 Antikörper (Biotin) (ABIN2689781)

Abrams: "Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies." in: Current protocols in immunology / edited by John E. Coligan ... [et al.], Vol. Chapter 6, pp. Unit 6.20, (2008) (PubMed).

Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." in: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, (1992) (PubMed).

Starnes, Pearce, Tewari, Yim, Zou, Abrams: "Anti-IL-6 monoclonal antibodies protect against lethal Escherichia coli infection and lethal tumor necrosis factor-alpha challenge in mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 145, Issue 12, pp. 4185-91, (1991) (PubMed).

Details zu IL-6

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Andere Bezeichnung: IL-6

Pathways: TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome