IL-6 Antikörper (Biotin)

Produktnummer ABIN2689780

Zitiert in 3+ Publikationen. Der Biotin-konjugierte Ratte Monoklonal anti-IL-6 Antikörper (Klon MQ2) (ABIN2689780) detektiert spezifisch IL-6 in WB, ELISA und Neut. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IL-6 Antikörper (Biotin) (ABIN2689780)

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL-6 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Neutralization (Neut)

Klon: MQ2

Produktdetails anti-IL-6 Antikörper (Biotin)

Produktmerkmale: The MQ2-39C3 antibody reacts with human interleukin-6 (IL-6). The immunogen used to generate the MQ2-39C3 hybridoma was recombinant human IL-6. This is a neutralizing antibody. This antibody is routinely tested by ELISA detection. Other applications were tested during antibody development only or reported in the literature.

BD Pharmingen™ Biotin Rat Anti-Human IL-6 - Biotin - Clone MQ2-39C3 - Isotype Rat IgG2a - Reactivity Hu - 0.5 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Recombinant human IL-6

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Referenzen für anti-IL-6 Antikörper (Biotin) (ABIN2689780)

Abrams: "Immunoenzymetric assay of mouse and human cytokines using NIP-labeled anti-cytokine antibodies." in: Current protocols in immunology / edited by John E. Coligan ... [et al.], Vol. Chapter 6, pp. Unit 6.20, (2008) (PubMed).

Gaines Das, Poole: "The international standard for interleukin-6. Evaluation in an international collaborative study." in: Journal of immunological methods, Vol. 160, Issue 2, pp. 147-53, (1993) (PubMed).

Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." in: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, (1992) (PubMed).

Details zu IL-6

Target: IL-6 (IL6) (Interleukin 6 (IL6))

Andere Bezeichnung: IL-6

Pathways: TLR Signalweg, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagie, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome