Caspase 8 Antikörper
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- Target Alle Caspase 8 (CASP8) Antikörper anzeigen
- Caspase 8 (CASP8)
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Reaktivität
- Human
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser Caspase 8 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Aufreinigung
- The antibody was purified by affinity chromatography
- Klon
- 1H10
- Isotyp
- IgG2a
- Top Product
- Discover our top product CASP8 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Upon receipt, store between 2°C and 8°C.
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- Target
- Caspase 8 (CASP8)
- Andere Bezeichnung
- Caspase-8 (CASP8 Produkte)
- Hintergrund
- Caspase-8 is involved in the apoptosis mediated by CD95 and TNFR-1. It is suggested that following the triggering of apoptosis by CD95 or TNFR-1, the adaptor molecule FADD interact physically with cytosolic caspase-8 and initiate the apoptotic cascade. The active caspase-8 consists of two subunits of p18 and p10. This antibody should recognize the whole length of human caspase-8 and some isofrms of lower MW.
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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