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CD40 Antikörper (PE-Cy7)

Name: CD40 Antikörper (PE-Cy7)
SKU: ABIN2659262
Price: 377.23 EUR
Availability: InStock

CD40 Reaktivität: Human FACS, IF Wirt: Maus Monoclonal 5C3 PE-Cy7

FACS

2 Abbildungen

Produktnummer ABIN2659262

Datenblatt (PDF)

Target Alle CD40 Antikörper anzeigen

CD40
Reaktivität
192

118

21

19

8

6

6

5

4

3

2

2

2

2

1
Human
Wirt
118

95

57

8

2

2

1
Maus
Passende Sekundärantikörper
Klonalität
191

83

7
Monoklonal
Konjugat
132

28

25

17

14

7

6

4

4

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD40 Antikörper ist konjugiert mit PE-Cy7
Applikation
172

92

63

54

38

35

22

22

17

14

13

12

8

6

5

5

4

4

4

4

4

4

3

3

2

2

2

1

1

1
Flow Cytometry (FACS), Immunofluorescence (IF)

Kreuzreaktivität

Pavian, Schimpanse, Cynomolgus, Rhesusaffen, Squirrel Monkey (Saimiri spec.)

Aufreinigung

The antibody was purified by affinity chromatography and conjugated with PE/Cy7 under optimal conditions. The solution is free of unconjugated PE/Cy7 and unconjugated antibody.

Klon

5C3

Isotyp

IgG1 kappa

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CD40 Reaktivität: Human WB, IF Wirt: Maus Monoclonal 41-CD40 unconjugated

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CD40 Reaktivität: Human, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-CD40 (CD40) (Extracellular Domain) antibody
CD40 Reaktivität: Human FACS, IHC, St Wirt: Maus Monoclonal 5C3 unconjugated

anti-CD40 (CD40) antibody
CD40 Reaktivität: Human FACS Wirt: Maus Monoclonal HI40a unconjugated

anti-CD40 (CD40) antibody (FITC)
CD40 Reaktivität: Human FACS Wirt: Maus Monoclonal HI40a FITC

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Buffer

Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Protect from prolonged exposure to light. Do not freeze.

Lagerung

4 °C

Informationen zur Lagerung

The antibody solution should be stored undiluted between 2°C and 8°C.
Target

CD40

Andere Bezeichnung

CD40 (CD40 Produkte)

Hintergrund

CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.

Pathways

NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints