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CD40 Antikörper (APC)

Name: CD40 Antikörper (APC)
SKU: ABIN2658660
Price: 156.85 EUR
Availability: InStock

CD40 Reaktivität: Maus ICFC Wirt: Ratte Monoclonal 3-23 APC

FACS

1 image

Produktnummer ABIN2658660

Datenblatt (PDF)

Target Alle CD40 Antikörper anzeigen

CD40
Reaktivität
192

120

21

19

8

6

6

5

4

3

2

2

2

2

1
Maus
Wirt
117

95

59

8

3

2

1
Ratte
Passende Sekundärantikörper
Klonalität
193

83

7
Monoklonal
Konjugat
135

27

25

16

13

7

6

4

4

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD40 Antikörper ist konjugiert mit APC
Applikation
174

92

63

54

38

32

23

22

17

14

13

12

8

6

5

5

4

4

4

4

4

4

3

3

2

2

2

1

1

1
Intracellular Flow Cytometry (ICFC)

Aufreinigung

The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Klon

3-23

Isotyp

IgG2a kappa

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

0.2 mg/mL

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Protect from prolonged exposure to light. Do not freeze.

Lagerung

4 °C

Informationen zur Lagerung

The antibody solution should be stored undiluted between 2°C and 8°C.
Target

CD40

Andere Bezeichnung

CD40 (CD40 Produkte)

Hintergrund

CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154(gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

Pathways

NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints