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CD40 Antikörper

CD40 Reaktivität: Maus, Ratte FACS, Func Wirt: Hamster Monoclonal HM40-3 unconjugated

Produktnummer ABIN2567687

Datenblatt (PDF)

Target Alle CD40 Antikörper anzeigen

CD40
Reaktivität
193

118

21

19

8

6

6

5

4

3

2

2

2

2

1
Maus, Ratte
Wirt
119

95

57

8

2

2

1
Hamster
Klonalität
192

83

7
Monoklonal
Konjugat
132

28

25

17

14

7

6

4

4

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD40 Antikörper ist unkonjugiert
Applikation
173

92

63

54

38

36

22

22

17

14

13

12

8

6

5

5

4

4

4

4

4

4

3

3

2

2

2

1

1

1
Flow Cytometry (FACS), Functional Studies (Func)

Spezifität

The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50.

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Klon

HM40-3

Isotyp

IgM kappa

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C. Do not freeze.
Target

CD40

Andere Bezeichnung

CD40 (CD40 Produkte)

Hintergrund

The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.

Gen-ID

21939

UniProt

P27512

Pathways

NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints