CD40 Antikörper

Produktnummer ABIN2567687

Dieses Hamster Monoklonal-Antikörper erkennt spezifisch CD40 in FACS und Func. Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für CD40 Antikörper (ABIN2567687)

Target: CD40

Reaktivität: Maus, Ratte

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser CD40 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Functional Studies (Func)

Klon: HM40-3

Produktdetails anti-CD40 Antikörper

Spezifität: The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50.

Aufreinigung: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Isotyp: IgM kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-buffered aqueous solution, ph7.2.

Lagerung: 4 °C

Informationen zur Lagerung: The product should be stored undiluted at 4°C. Do not freeze.

Details zu CD40

Target: CD40

Andere Bezeichnung: CD40

Hintergrund: The HM40-3 monoclonal antibody reacts with mouse CD40, a 48kDA type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.

Gen-ID: 21939

UniProt: P27512

Pathways: NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints