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CD40 Antikörper (FITC)

CD40 Reaktivität: Human FACS Wirt: Maus Monoclonal 5C3 FITC

Produktnummer ABIN2567684

Datenblatt (PDF)

Target Alle CD40 Antikörper anzeigen

CD40
Reaktivität
192

120

21

19

8

6

6

5

4

3

2

2

2

2

1
Human
Wirt
117

95

59

8

3

2

1
Maus
Passende Sekundärantikörper
Klonalität
193

83

7
Monoklonal
Konjugat
135

27

25

16

13

7

6

4

4

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD40 Antikörper ist konjugiert mit FITC
Applikation
174

92

63

54

38

32

23

22

17

14

13

12

8

6

5

5

4

4

4

4

4

4

3

3

2

2

2

1

1

1
Flow Cytometry (FACS)

Spezifität

The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein.

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Klon

5C3

Isotyp

IgG1 kappa

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target

CD40

Andere Bezeichnung

CD40 (CD40 Produkte)

Hintergrund

The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The 5C3 antibody partially blocks the binding of CD40L (CD154). In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation.

Gen-ID

958

UniProt

P25942

Pathways

NF-kappaB Signalweg, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints