CD14 Antikörper (APC)
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- Target Alle CD14 Antikörper anzeigen
- CD14
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD14 Antikörper ist konjugiert mit APC
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells.
- Aufreinigung
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Klon
- 61D3
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD14 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- Target
- CD14
- Andere Bezeichnung
- CD14 (CD14 Produkte)
- Hintergrund
- The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB.
- Gen-ID
- 929
- UniProt
- P08571
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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