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CD11b Antikörper (Activation Domain)

Name: CD11b Antikörper (Activation Domain)
SKU: ABIN2567135
Price: 763.13 EUR
Availability: InStock

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD11b in FACS und Func. Er zeigt eine Reaktivität gegenüber Human.

Produktnummer ABIN2567135

Kurzübersicht für CD11b Antikörper (Activation Domain) (ABIN2567135)

Target

Alle CD11b (ITGAM) Antikörper anzeigen

CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reaktivität

Human

Wirt

Maus

Klonalität

Monoklonal

Konjugat

Dieser CD11b Antikörper ist unkonjugiert

Applikation

Flow Cytometry (FACS), Functional Studies (Func)

Klon

CBRM1-5

Discover our top product ITGAM Primärantikörper

Bindungsspezifität
34

16

14

8

6

5

5

5

4

3

3

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Activation Domain

Spezifität

The CBRM1/5 monoclonal antibody binds with the 165 kDa human adhesion glycoprotein CD11b, which forms, together with the 95 kDa CD18 (integrin β2) a complex known as Mac-1.

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Isotyp

IgG1 kappa
anti-Integrin alpha M (ITGAM) (AA 145-340) antibody
ITGAM Reaktivität: Human IHC, WB, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) (AA 520-570) antibody
ITGAM Reaktivität: Human, Maus, Ratte FACS Wirt: Kaninchen Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) (AA 253-282), (N-Term) antibody
ITGAM Reaktivität: Human FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal RB17991 unconjugated

anti-Integrin alpha M (ITGAM) (AA 77-180) antibody
ITGAM Reaktivität: Human, Maus, Ratte FACS, WB, IHC (fro), ELISA, IHC (p), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) (AA 31-160) antibody
ITGAM Reaktivität: Ratte IHC, WB, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) antibody (FITC)
ITGAM Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-174 FITC

anti-Integrin alpha M (ITGAM) antibody (Biotin)
ITGAM Reaktivität: Human FACS, IP Wirt: Maus Monoclonal MEM-174 Biotin

anti-Integrin alpha M (ITGAM) antibody (PE)
ITGAM Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-174 PE

anti-Integrin alpha M (ITGAM) (AA 623-728) antibody
ITGAM Reaktivität: Human ELISA, ICC Wirt: Maus Monoclonal 3A10H5 unconjugated

anti-Integrin alpha M (ITGAM) (AA 941-1074) antibody
ITGAM Reaktivität: Human IHC, WB, StM Wirt: Maus Monoclonal ITGAM-3338 unconjugated

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C. Do not freeze.
Target

CD11b (ITGAM) (Integrin alpha M (ITGAM))

Andere Bezeichnung

CD11b

Hintergrund

The CBRM1/5 monoclonal antibody binds with the 165 kDa human adhesion glycoprotein CD11b, which forms, together with the 95 kDa CD18 (integrin β2) a complex known as Mac-1. CD11b is expressed on the surface of activated lymphocytes, a subset of natural killer cells, granulocytes, and monocytes. It functions as a receptor in cell-cell and cell-matrix interactions and as a receptor for iC3b, ICAM-1, ICAM-2, and ICAM-3 intercellular adhesion molecules. The CBRM1/5 specifically reacts with the activation-specific epitope of the Mac-1 Molecule, in the I domain on the alpha chain near the ligand binding site. The antibody has been reported to inhibit the cellular adhesion mediated by Mac-1.

Gen-ID

3684

UniProt

P11215

Pathways

Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation