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p21 Antikörper

CDKN1A Reaktivität: Human WB, IP Wirt: Maus Monoclonal WA-1 unconjugated
Produktnummer ABIN2475991
  • Target Alle p21 (CDKN1A) Antikörper anzeigen
    p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
    Reaktivität
    • 240
    • 121
    • 97
    • 36
    • 12
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 208
    • 51
    • 1
    Maus
    Klonalität
    • 202
    • 57
    • 1
    Monoklonal
    Konjugat
    • 104
    • 17
    • 15
    • 15
    • 10
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser p21 Antikörper ist unkonjugiert
    Applikation
    • 158
    • 93
    • 66
    • 66
    • 66
    • 57
    • 51
    • 41
    • 41
    • 33
    • 19
    • 14
    • 12
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Spezifität
    This antibody recognises the human cyclin-dependent kinase inhibitor p21/WAF1, which is an important cell cycle regulatory protein, also known as CIP1.The p21 protein inhibits cell cycle progression at both the G1 and G2 checkpoints. The expression of p21 is inducible by a wide range of stress stimuli.This antibody detects a band of approximately 21kD in MCF-7 cell lysates following UV radiation.
    Produktmerkmale
    Purified IgG
    Aufreinigung
    Purified
    Immunogen
    Human p21 protein
    Klon
    WA-1
    Isotyp
    IgG1
    Top Product
    Discover our top product CDKN1A Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
  • Kotala, Uldrijan, Horky, Trbusek, Strnad, Vojtesek: "Potent induction of wild-type p53-dependent transcription in tumour cells by a synthetic inhibitor of cyclin-dependent kinases." in: Cellular and molecular life sciences : CMLS, Vol. 58, Issue 9, pp. 1333-9, (2001) (PubMed).

    Kolár, Murray, Scott, Harrison, Vojt?sek, Dusek: "Relation of Bcl-2 expression to androgen receptor, p21WAF1/CIP1, and cyclin D1 status in prostate cancer." in: Molecular pathology : MP, Vol. 53, Issue 1, pp. 15-8, (2000) (PubMed).

  • Target
    p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
    Andere Bezeichnung
    p21/WAF1 (CDKN1A Produkte)
    Gen-ID
    1026
    UniProt
    P38936
    Pathways
    p53 Signalweg, PI3K-Akt Signalweg, Zellzyklus, AMPK Signaling, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagie
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