p21 Antikörper
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- Target Alle p21 (CDKN1A) Antikörper anzeigen
- p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser p21 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP)
- Spezifität
- This antibody recognises the human cyclin-dependent kinase inhibitor p21/WAF1, which is an important cell cycle regulatory protein, also known as CIP1.The p21 protein inhibits cell cycle progression at both the G1 and G2 checkpoints. The expression of p21 is inducible by a wide range of stress stimuli.This antibody detects a band of approximately 21kD in MCF-7 cell lysates following UV radiation.
- Produktmerkmale
- Purified IgG
- Aufreinigung
- Purified
- Immunogen
- Human p21 protein
- Klon
- WA-1
- Isotyp
- IgG1
- Top Product
- Discover our top product CDKN1A Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.0 mg/mL
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Potent induction of wild-type p53-dependent transcription in tumour cells by a synthetic inhibitor of cyclin-dependent kinases." in: Cellular and molecular life sciences : CMLS, Vol. 58, Issue 9, pp. 1333-9, (2001) (PubMed).
: "Relation of Bcl-2 expression to androgen receptor, p21WAF1/CIP1, and cyclin D1 status in prostate cancer." in: Molecular pathology : MP, Vol. 53, Issue 1, pp. 15-8, (2000) (PubMed).
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Potent induction of wild-type p53-dependent transcription in tumour cells by a synthetic inhibitor of cyclin-dependent kinases." in: Cellular and molecular life sciences : CMLS, Vol. 58, Issue 9, pp. 1333-9, (2001) (PubMed).
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- Target
- p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
- Andere Bezeichnung
- p21/WAF1 (CDKN1A Produkte)
- Gen-ID
- 1026
- UniProt
- P38936
- Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Zellzyklus, AMPK Signaling, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagie
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