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CD11b Antikörper

ITGAM Reaktivität: Ratte FACS, IHC, IP, IHC (fro) Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN217775
  • Target Alle CD11b (ITGAM) Antikörper anzeigen
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reaktivität
    • 286
    • 187
    • 74
    • 31
    • 20
    • 19
    • 17
    • 14
    • 11
    • 10
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    Ratte
    Wirt
    • 166
    • 122
    • 106
    • 2
    • 1
    • 1
    Maus
    Klonalität
    • 299
    • 95
    • 2
    Monoklonal
    Konjugat
    • 128
    • 41
    • 32
    • 29
    • 20
    • 10
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD11b Antikörper ist unkonjugiert
    Applikation
    • 300
    • 89
    • 88
    • 83
    • 63
    • 49
    • 39
    • 25
    • 23
    • 21
    • 14
    • 14
    • 13
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    Recognizes the rat equivalent of human CD11b, the receptor for the iC3b component of complement. The antigen is expressed on most macrophages, including resident and activated peritoneal macrophages and Kupffer cells and around 35 % of alveolar macrophages. The antibody also labels dendritic cells, granulocytes and microglial cells in the brain. Clone MRC OX-42 has been reported as being suitable for use on paraffin-embedded material following PLP fixation (periodate-lysine-paraformaldehyde). Functionally, clone OX-42 inhibits complement mediated rosettes(1).
    Aufreinigung
    Protein G purified
    Endotoxin-Niveau
    Low Endotoxin
    Immunogen
    Rat peritoneal macrophages.

    Type of Immunogen: Cells
    Isotyp
    IgG2a
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  • Applikationshinweise
    Approved: Flo (1:50 - 1:100), IHC, IHC-Fr (1:50 - 1:100), IP

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
    Kommentare

    Target Species of Antibody: Rat

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    PBS,  pH 7.2.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and freeze at -20°C. Avoid freeze-thaw cycles.
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Andere Bezeichnung
    ITGAM / CD11b (ITGAM Produkte)
    Hintergrund
    Name/Gene ID: ITGAM
    Family: Integrin

    Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain
    Gen-ID
    3684
    Pathways
    Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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