CD14 Antikörper (FITC)

Produktnummer ABIN217703

Der Maus Monoklonal Anti-CD14 Antikörper wurde für FACS validiert. Er ist geeignet, CD14 in Proben von Human, Cynomolgus und Rhesusaffen zu detektieren.

Kurzübersicht für CD14 Antikörper (FITC) (ABIN217703)

Target: CD14

Reaktivität: Human, Cynomolgus, Rhesusaffen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD14 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Produktdetails anti-CD14 Antikörper (FITC)

Spezifität: Recognizes a cell surface antigen of 55 kD, known as CD14. The CD14 Molecule is found predominantly on monocytes and macrophages in flow cytometry, it is less strongly expressed on granulocytes, and is absent from stem cells and myeloid cells of very early differentiation states. In immunohistology the CD14 Molecule is found to be present on Langerhans cells, follicular dendritic cells, histiocytes and high endothelial venules. Antibodies to the CD14 Molecule are known to induce oxidative burst formation. In tonsil tissue sections UCHM1 gives positive staining reactions with monocytic cells, the interfollicular tissue macrophages seen under the capsule, and dendritic reticulum cells. Skin Langerhans cells are always negative. UCHM1 Reacts with Kupffer cells and sinus lining cells on the liver.

Aufreinigung: Protein G purified

Immunogen: Human Thymocytes followed by peripheral blood mononuclear cells.

Type of Immunogen: Cells

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Approved: Flo (1:1 - 1:10)

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu CD14

Target: CD14

Andere Bezeichnung: CD14

Hintergrund: Name/Gene ID: CD14

Synonyms: CD14, CD14 Molecule, CD14 antigen

Gen-ID: 929

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades