CD14 Antikörper

Produktnummer ABIN217653

Dieses Anti-CD14-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD14 in FACS, WB, ELISA und Func. Geeignet für Human, Cynomolgus, Schwein, Rind (Kuh), Schaf, Hund, Kaninchen, Ziege, Cat, Nerz und Llama.

Kurzübersicht für CD14 Antikörper (ABIN217653)

Target: CD14

Reaktivität: Human, Cynomolgus, Schwein, Rind (Kuh), Schaf, Hund, Kaninchen, Ziege, Cat, Nerz, Llama

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD14 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Functional Studies (Func)

Klon: TÜK4

Produktdetails anti-CD14 Antikörper

Spezifität: Recognizes the human CD14 cell surface antigen. CD14 is a 55 KDa glycoprotein that contains multiple leucine-rich repeats. It is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) linkage but a soluble form of CD14 also exists. CD14 is strongly expressed on the surface of monocytes and macrophages but has also been shown to be expressed on the surface of non-myeloid cells. CD14 functions as a pattern recognition receptor, in innate immunity for a variety of ligands, in particular for the LPS (endotoxin) of Gram-negative bacteria. Has been shown to block SDF-induced chemotaxis of U937 cells in a dose-dependent manner.

Aufreinigung: Protein G purified

Endotoxin-Niveau: Low Endotoxin

Immunogen:

Type of Immunogen: Native protein

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, Flo (1:100 - 1:200), Func, WB

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS.

Handhabung: Store undiluted.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C. Store undiluted.

Details zu CD14

Target: CD14

Andere Bezeichnung: CD14

Hintergrund: Name/Gene ID: CD14

Synonyms: CD14, CD14 Molecule, CD14 antigen

Gen-ID: 929

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades