CD11b Antikörper

Produktnummer ABIN213152

Der Maus Monoklonal Anti-CD11b-Antikörper wurde für FACS, IHC und IHC (fro) validiert. Er ist geeignet, CD11b in Proben von Ratte zu detektieren.

Kurzübersicht für CD11b Antikörper (ABIN213152)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD11b Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: ED7

Produktdetails anti-CD11b Antikörper

Spezifität: Recognizes a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes. Like ED8, Recognizes small ramified microglia in the central nervous system. No other cell types are positive for ED7, except for the cilia of the bronchus epithelium. The recognized antigen is a heterodimer (160 and 95kD) belonging to the family of adhesion molecules (CD11b/CD18). ED7 and ED8 may recognize closely related epitopes on the same molecule. ED7 and ED8 have been shown to induce homotypic aggregation of granulocytes.

Aufreinigung: Protein A purified

Immunogen: Rat spleen cell homogenate.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: Flo, IHC, IHC-Fr (1:500)

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.

Kommentare:

Target Species of Antibody: Rat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: deionized water

Konzentration: Lot specific

Buffer: PBS, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Andere Bezeichnung: ITGAM / CD11b

Hintergrund: Name/Gene ID: ITGAM
Family: Integrin

Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

Gen-ID: 3684

UniProt: P11215

Pathways: Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation