CD11b Antikörper (Biotin)
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- Target Alle CD11b (ITGAM) Antikörper anzeigen
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Reaktivität
- Human, Maus, Kaninchen
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD11b Antikörper ist konjugiert mit Biotin
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- Recognizes the murine CD11b cell surface antigen (also known as the alpha M integrin chain or MAC-1), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Clone M1/70.15 has been reported to block iC3b binding to its receptor. * Clone M1/70.15 has been reported to as being suitable for use on PLP fixed paraffin embedded tissue but has not been tested for use on formalin fixed tissue. This product is routinely tested in flow cytometry on mouse peritoneal macrophages.
- Aufreinigung
- Protein G purified
- Immunogen
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T cell enriched splenocytes from B10 mice.
Type of Immunogen: Cells - Isotyp
- IgG2b
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- Discover our top product ITGAM Primärantikörper
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- Applikationshinweise
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Approved: Flo (1:1)
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - Kommentare
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Target Species of Antibody: Mouse
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Rekonstitution
- deionized water
- Konzentration
- Lot specific
- Buffer
- 0.09 % sodium azide, 1 % BSA.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeat freeze-thaw cycles.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Andere Bezeichnung
- ITGAM / CD11b (ITGAM Produkte)
- Hintergrund
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Name/Gene ID: ITGAM
Family: Integrin
Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain - Gen-ID
- 3684
- UniProt
- P11215
- Pathways
- Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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