TLR4 Antikörper

Produktnummer ABIN198156

Dieses Anti-TLR4-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von TLR4 in FACS und IP. Geeignet für Maus.

Kurzübersicht für TLR4 Antikörper (ABIN198156)

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser TLR4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP)

Produktdetails anti-TLR4 Antikörper

Spezifität: Reacts preferentially, especially in flow cytometry, with mouse TLR4 that is associated with MD-2. Recognizes the mouse TLR4/MD-2 complex and is not useful for detection of TLR4 alone.

Aufreinigung: Purified

Immunogen:

Type of Immunogen: Native protein

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Approved: Flo (1:10), IP

Usage: Can be used for Flow Cytometry and Immunoprecipitation. The antibody recognizes the mouse TLR4/MD-2 complex and is not useful for detection of TLR4 alone. Furthermore the antibody can be used as antagonist for TLR4, it blocks LPS-induced cytokine production. Flow Cytometry: 1:10. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions.

Kommentare:

Target Species of Antibody: Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.02 % sodium azide, 0.1 % BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Details zu TLR4

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Andere Bezeichnung: TLR4

Hintergrund: Name/Gene ID: TLR4
Family: Toll-like Receptor

Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll

Gen-ID: 7099

UniProt: O00206

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteine