TLR4 Antikörper

Produktnummer ABIN198155

Der Maus-Monoklonal Anti-TLR4-Antikörper wurde für FACS, IHC, IP, Neut und IHC (fro) validiert. Er ist geeignet zum Nachweis von TLR4 in Proben aus Human und Affe. }

Kurzübersicht für TLR4 Antikörper (ABIN198155)

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Reaktivität: Human, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TLR4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Neutralization (Neut), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: HTA125

Produktdetails anti-TLR4 Antikörper

Spezifität: Reacts preferentially, especially in Flow Cytometry, with human TLR4 (CD284) that is associated with MD-2. This clone is a TLR4 (CD284) function-blocking antibody that is useful for studies on the role of TLR4 (CD284) as a receptor for LPS induced cytokine production by TLR4 bearing cells. The antibody was shown to precipitate TLR4 (100kD).

Aufreinigung: Purified

Immunogen: Human TLR4.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Approved: Flo, IHC, IHC-Fr, IP, Neut

Usage: Suitable for use in Flow Cytometry, Immunoprecipitation, and Neutralization (can be used as antagonist for TLR4, it blocks LPS-induced cytokine production). Note: Before use in biological assays, the product must be sterile-filtered and depending on the concentration to be used, dialyzed against culture medium to remove the sodium azide added.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.1 % BSA, 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu TLR4

Target: TLR4 (Toll-Like Receptor 4 (TLR4))

Andere Bezeichnung: TLR4

Hintergrund: Name/Gene ID: TLR4
Family: Toll-like Receptor

Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll

Gen-ID: 7099

UniProt: O00206

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteine