AKR1C1 Antikörper (AA 22-218)

Produktnummer ABIN1886214

Der Kaninchen Polyklonal anti-AKR1C1 Antikörper (ABIN1886214) detektiert spezifisch AKR1C1 in WB, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für AKR1C1 Antikörper (AA 22-218) (ABIN1886214)

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR1C1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-AKR1C1 Antikörper

Bindungsspezifität: AA 22-218

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 22 and 218 of Human AKR1C1

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu AKR1C1

Target: AKR1C1 (DDH) (Dihydrodiol Dehydrogenase (DDH))

Andere Bezeichnung: AKR1C1

Hintergrund: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins.These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors.The enzymes display overlapping but distinct substrate.This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.[provided by RefSeq]

Molekulargewicht: 37 kDa

Gen-ID: 1645

NCBI Accession: NP_001344, NM_001353

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process