TRADD Antikörper (AA 1-13)
Kurzübersicht für TRADD Antikörper (AA 1-13) (ABIN1885603)
Target
Alle TRADD Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-13
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Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 13 of TRADD
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Applikationshinweise
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 1 x PBS, 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
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Andere Bezeichnung
- TRADD
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Hintergrund
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The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation.This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis.This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.[provided by RefSeq]
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Molekulargewicht
- 34 kDa
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Gen-ID
- 8717
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NCBI Accession
- NM_003789, NP_003780
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Pathways
- NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Hepatitis C
Target
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