MAVS Antikörper (N-Term)
(1 reference)Kurzübersicht für MAVS Antikörper (N-Term) (ABIN1881530)
Target
Alle MAVS Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-30, N-Term
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This Mouse Mavs antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Mavs.
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Isotyp
- Ig Fraction
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anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-65) antibody
MAVS Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 34-96) antibodyMAVS Reaktivität: Human WB, IHC, ICC, IHC (fro), FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (C-Term) antibodyMAVS Reaktivität: Human, Maus WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 160-450) antibodyMAVS Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal Adri-1 unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 1-540) antibodyMAVS Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (N-Term) antibodyMAVS Reaktivität: Human, Maus, Rind (Kuh) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 477-505), (C-Term) antibodyMAVS Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB33921 unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 470-519) antibodyMAVS Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 146-195) antibodyMAVS Reaktivität: Human, Maus, Rind (Kuh) WB Wirt: Kaninchen Polyclonal unconjugated
anti-Mitochondrial Antiviral Signaling Protein (MAVS) (AA 477-505) antibodyMAVS Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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: "Influenza virus activates inflammasomes via its intracellular M2 ion channel." in: Nature immunology, Vol. 11, Issue 5, pp. 404-10, (2010) (PubMed).
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: "Influenza virus activates inflammasomes via its intracellular M2 ion channel." in: Nature immunology, Vol. 11, Issue 5, pp. 404-10, (2010) (PubMed).
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- MAVS (Mitochondrial Antiviral Signaling Protein (MAVS))
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Andere Bezeichnung
- Mavs
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Hintergrund
- Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity).
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Molekulargewicht
- 53399
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NCBI Accession
- NP_001193314, NP_659137
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UniProt
- Q8VCF0
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Pathways
- Activation of Innate immune Response, Inositol Metabolic Process, Hepatitis C
Target
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