Caspase 9 Antikörper (N-Term)
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- Target Alle Caspase 9 (CASP9) Antikörper anzeigen
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Caspase 9 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sterilität
- 0.2 μm filtered
- Immunogen
- Synthetic peptide corresponding to amino acids 2 to 22 of human caspase-9.
- Klon
- LAP6-96
- Isotyp
- IgG1
- Top Product
- Discover our top product CASP9 Primärantikörper
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- Applikationshinweise
- Western Blot The optimal dilution for a specific application should be determined by the researcher.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Mouse monoclonal antibody against human Caspase-9 (cysteine-requiring aspartate protease-9). Available in 100 µl vials at a concentration of 1 mg/ml (100 µg) in PBS with 0.08% sodium azide. Purified by 0.2 µm sterile filtration.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
- Andere Bezeichnung
- Caspase-9 (CASP9 Produkte)
- Synonyme
- CASP9 antikoerper, AI115399 antikoerper, APAF-3 antikoerper, AW493809 antikoerper, CASP-9 antikoerper, Caspase-9 antikoerper, ICE-LAP6 antikoerper, Mch6 antikoerper, Apaf3 antikoerper, Casp-9-CTD antikoerper, Casp9_v1 antikoerper, Ice-Lap6 antikoerper, APAF3 antikoerper, MCH6 antikoerper, PPP1R56 antikoerper, caspase 9 antikoerper, CASP9 antikoerper, Casp9 antikoerper
- Hintergrund
- Caspases are key effectors of programmed cell death. They are synthesized as inactive pro-enzymes, which are activated by cleavage at a specific aspartate residue to form two subunits. These subunits are normally linked together by a linker, which may be involved in the regulation of the different caspases. Caspase-9 is a member of the CED-3 family and is very similar to caspase-3. Pro-caspase-9 can be activated by either caspase-3 or granzyme B, although they cleave the pro-enzyme to different size subunits. Cleavage by granzyme B produces an active enzyme, which is capable of cleaving PARP. Also, the ability of caspase-3 to activate caspase-9 seems to suggest that caspase-9 is further downstream of caspase-3 and may be involved in later changes in cells observed undergoing apoptosis.
- Pathways
- MAPK Signalweg, RTK Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Endopeptidase Activity
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