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CD11b Antikörper (PE)

ITGAM Reaktivität: Human, Maus FACS Wirt: Ratte Monoclonal 5C6 PE
Produktnummer ABIN1820250
  • Target Alle CD11b (ITGAM) Antikörper anzeigen
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reaktivität
    • 286
    • 187
    • 74
    • 31
    • 20
    • 19
    • 17
    • 14
    • 11
    • 10
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    Human, Maus
    Wirt
    • 166
    • 122
    • 106
    • 2
    • 1
    • 1
    Ratte
    Klonalität
    • 299
    • 95
    • 2
    Monoklonal
    Konjugat
    • 128
    • 41
    • 32
    • 29
    • 20
    • 10
    • 8
    • 8
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD11b Antikörper ist konjugiert mit PE
    Applikation
    • 300
    • 89
    • 88
    • 83
    • 63
    • 49
    • 39
    • 25
    • 23
    • 21
    • 14
    • 14
    • 13
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    Recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. Clone 5C6 immunoprecipitates a heterodimer of 165 and 95kD. Clone 5C6 also exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. This clone also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.
    Aufreinigung
    Ion exchange chromatography
    Immunogen
    Thioglycollate-elicited Peritoneal Macrophages (TPM).
    Klon
    5C6
    Isotyp
    IgG2b
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  • Applikationshinweise
    Approved: Flo (1:10)

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
    Kommentare

    Target Species of Antibody: Mouse

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Rekonstitution
    Distilled water
    Konzentration
    Lot specific
    Buffer
    PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing. Protect from light.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Andere Bezeichnung
    ITGAM / CD11b (ITGAM Produkte)
    Hintergrund
    Name/Gene ID: ITGAM
    Family: Integrin

    Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain
    Gen-ID
    3684
    Pathways
    Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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