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CD11b Antikörper

ITGAM Reaktivität: Human, Maus FACS, IHC, IP, IF, IHC (fro), Func Wirt: Ratte Monoclonal 5C6 unconjugated

Produktnummer ABIN1820248

Datenblatt (PDF)

Target Alle CD11b (ITGAM) Antikörper anzeigen

CD11b (ITGAM) (Integrin alpha M (ITGAM))
Reaktivität
286

187

74

31

20

19

17

14

11

10

7

4

4

2

2

1
Human, Maus
Wirt
166

122

106

2

1

1
Ratte
Passende Sekundärantikörper
Klonalität
299

95

2
Monoklonal
Konjugat
128

41

32

29

20

10

8

8

7

7

5

5

5

5

5

5

5

4

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
Dieser CD11b Antikörper ist unkonjugiert
Applikation
300

89

88

83

63

49

39

25

23

21

14

14

13

6

5

5

5

4

4

3

2

2

2

2

2

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Spezifität

Recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. The antibody immunoprecipitates a heterodimer of 165 and 95kD. Clone 5C6 exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. Clone 5C6 also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.

Aufreinigung

Protein G purified

Endotoxin-Niveau

Low Endotoxin

Immunogen

Thioglycollate-elicited Peritoneal Macrophages (TPM).

Klon

5C6

Isotyp

IgG2b

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Applikationshinweise

Approved: Flo (1:50 - 1:100), Func, IF, IHC, IHC-Fr, IP

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Kommentare

Target Species of Antibody: Mouse

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

PBS

Handhabung

Avoid repeated freezing and thawing.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Avoid freeze-thaw cycles.
Target

CD11b (ITGAM) (Integrin alpha M (ITGAM))

Andere Bezeichnung

ITGAM / CD11b (ITGAM Produkte)

Hintergrund

Name/Gene ID: ITGAM
Family: Integrin

Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

Gen-ID

3684

Pathways

Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation