CD14 Antikörper
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- Target Alle CD14 Antikörper anzeigen
- CD14
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Reaktivität
- Human, Rind (Kuh), Schaf, Water Buffalo
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD14 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Spezifität
- Recognizing bovine CD14, a GPI-anchored membrane glycoprotein and monocyte/macrophage differentiation antigen, belonging to the lipopolysaccharide receptor family, also expressed weakly on microglia and Langerhans cells. CD14 acts as a receptor for the potent bacterial endotoxin, lipopolysaccharide (LPS), facilitated by LPS-binding protein (LBP). The binding of LPS to CD14 results in cell activation and the release of cytokines and the inflammatory response, and has been shown to upregulate the cell surface expression of adhesion molecules. Cross-reacts with human CD14 expressed on transfected COS-7 cells, and also recognizes an epitope on ovine CD14, see for details. CC-G33 has also been shown to be reactive with CD14 from the Water buffalo.
- Aufreinigung
- Protein G purified
- Immunogen
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Partially purified polypeptides isolated from bovine leucocyte cell surface membrane.
Type of Immunogen: Purified protein - Klon
- CC-G33
- Isotyp
- IgG1
- Top Product
- Discover our top product CD14 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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Target Species of Antibody: Bovine
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- CD14
- Andere Bezeichnung
- CD14 (CD14 Produkte)
- Hintergrund
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Name/Gene ID: CD14
Synonyms: CD14, CD14 Molecule, CD14 antigen - Gen-ID
- 929
- UniProt
- P08571
- Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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