CD14 Antikörper

Produktnummer ABIN1819121

Der Maus Monoklonal Anti-CD14-Antikörper wurde für FACS und IF validiert. Er ist geeignet, CD14 in Proben von Human, Rind (Kuh), Schaf und Water Buffalo zu detektieren.

Kurzübersicht für CD14 Antikörper (ABIN1819121)

Target: CD14

Reaktivität: Human, Rind (Kuh), Schaf, Water Buffalo

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD14 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: CC-G33

Produktdetails anti-CD14 Antikörper

Spezifität: Recognizing bovine CD14, a GPI-anchored membrane glycoprotein and monocyte/macrophage differentiation antigen, belonging to the lipopolysaccharide receptor family, also expressed weakly on microglia and Langerhans cells. CD14 acts as a receptor for the potent bacterial endotoxin, lipopolysaccharide (LPS), facilitated by LPS-binding protein (LBP). The binding of LPS to CD14 results in cell activation and the release of cytokines and the inflammatory response, and has been shown to upregulate the cell surface expression of adhesion molecules. Cross-reacts with human CD14 expressed on transfected COS-7 cells, and also recognizes an epitope on ovine CD14, see for details. CC-G33 has also been shown to be reactive with CD14 from the Water buffalo.

Aufreinigung: Protein G purified

Immunogen: Partially purified polypeptides isolated from bovine leucocyte cell surface membrane.

Type of Immunogen: Purified protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Target Species of Antibody: Bovine

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles.

Details zu CD14

Target: CD14

Andere Bezeichnung: CD14

Hintergrund: Name/Gene ID: CD14

Synonyms: CD14, CD14 Molecule, CD14 antigen

Gen-ID: 929

UniProt: P08571

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades