Complement Factor B Antikörper (Fragment Ba)

Produktnummer ABIN181128

Produktdetails anti-Complement Factor B Antikörper

Target: Complement Factor B (CFB)

Bindungsspezifität: Fragment Ba

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Complement Factor B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Spezifität: This antibody recognises the 30 kDa Ba fragment of 90 kDa complement factor B, present in blood serum.

Produktmerkmale: Synonyms: Properdin factor B, C3/C5 convertase, PBF2, CFB, BF, BFD, Glycine-rich beta glycoprotein

Aufreinigung: Affinity chromatography on Protein A

Immunogen: Purified human complement factor b.

Klon: 014III-33-2-4-3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot. Functional Assays. Flow Cytometry. ELISA: This antibody binds both the Ba fragment and the whole protein so is not suitablefor all ELISA applications. Immunohistochemistry on frozen sections. Recommended Positiv Control: Kidney from post streptoccal glomerulonephritis patients.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0mg/mL

Buffer: Borate buffered saline pH 8.2 - 8.4 containing 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Complement Factor B

Target: Complement Factor B (CFB)

Andere Bezeichnung: Complement Factor B (CFB Produkte)

Synonyme: AHUS4 antikoerper, BF antikoerper, BFD antikoerper, CFAB antikoerper, FB antikoerper, FBI12 antikoerper, GBG antikoerper, H2-Bf antikoerper, PBF2 antikoerper, bf antikoerper, Bf-1 antikoerper, Brre-Bf antikoerper, zgc:114032 antikoerper, Bf antikoerper, Sp152 antikoerper, bfb-A antikoerper, Bf B antikoerper, LOC397725 antikoerper, bf/c2 antikoerper, CFB antikoerper, AI195813 antikoerper, AI255840 antikoerper, B antikoerper, C2 antikoerper, Fb antikoerper, Da1-24 antikoerper, complement factor B antikoerper, complement factor B S homeolog antikoerper, complement factor B L homeolog antikoerper, CFB antikoerper, cfb antikoerper, bf antikoerper, cfb.S antikoerper, cfb.L antikoerper, bf/c2 antikoerper, LOC100555981 antikoerper, Cfb antikoerper

Hintergrund: C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit), leaving the 63 kDa Bb subunit associated with C3b, forming C3 convertase. Subunit Ba inhibits lymphocyte proliferation. Conversely, subunit Bb is involved in the proliferation of preactivated B lymphocytes.Synonyms: BF, BFD, C3/C5 convertase, CFB, Glycine-rich beta glycoprotein, PBF2, Properdin factor B

Gen-ID: 629

UniProt: P00751

Pathways: Komplementsystem, Proton Transport, Ribonucleoside Biosynthetic Process